Apart from the oral manifestations mentioned above, patients with multiple myeloma are more prone to get post-operative haemorrhage due to thrombocytopenia. Development of oral amyloidosis is a complication of the disease and suggests a grave prognosis.

Aplastic Anaemia
Bleeding tendency following oral surgical procedures and increased susceptibility to infection.

Sickle cell Anaemia
Pale oral mucosa, manifestation of jaundice, delayed eruption and hypoplasia of teeth and radiolucencies of the jaws in radiographs, more apparent between the roots of teeth where the trabeculae appear horizontal (step ladder pattern). Skull radiographs show the trabeculae which are oriented perpendicular to the inner and outer tables (hair on end appearance). Patients with sickle cell anaemia are more prone to develop osteomyelitis.

Thalassaemia.

Acute leukemia :
Some of the common oral manifestations are gingival bleeding, swelling, purpura, oral ulceration, lymphadinopathy, tonsillar swelling, infections such as candidiasis and HSV. Side effects of drugs used Rx are menifested as oral ulceration. dry mouth etc. There may be alveolar bone destruction as seen in radiographs.

Oral surgical procedures can result in excessive post-operative haemorrhage. So platelet infusion or blood transfusion may be required.